Pioneering Epigenetics Through Collaborative Science
We offer DNA methylation services to academic researchers, healthcare providers, clinical institutions, and industry leaders.
Our Services
Our offerings include the Infinium Methylation Screening Array (MSA), the Infinium MethylationEPIC v2.0 Array, and several custom arrays. Each platform is designed to meet specific research needs, from large-scale population studies to in-depth epigenetic investigations. Our epigenomic services provide comprehensive insights into DNA methylation patterns and their implications for health and disease.
Array Sequencing
Whole Genome Bisulfite Sequencing
Our bioinformatics team can assist you in analyzing research data, integrating multi-omic data sets into your research, optimizing data collection from study participants, and even writing your final manuscript. We provide the expertise to turn complex data into actionable insights.
Bioinformatic Analysis: Advanced computational tools to interpret complex biological data.
We offer two primary options for genomic investigations, along with customizable data processing and bioinformatics analytics services. Explore genomic DNA (gDNA) analysis and high-density genotyping using the Illumina GSA v4 array with advanced coverage of clinically relevant variants like significantly enhanced APOE calls.
Genotyping
Benefits of Partnership
High-Throughput, CLIA-Certified Precision
Process large sample volumes with CAP-compliant accuracy — up to $50 cheaper per sample than university labs. Our specialized DNA methylation workflows ensure precision, compliance, and scale.
Fast Turnaround Time
Optimized workflows deliver results in 2–4 weeks from sample receipt — helping you move from collection to insights without delay.
Sample & Array Flexibility
We process diverse tissue types — including blood, saliva, and solid tissue — and design custom or standard arrays to meet your study’s needs.
High-Throughput, CLIA-Certified Precision
Process large sample volumes with CAP-compliant accuracy — up to $50 cheaper per sample than university labs. Our specialized DNA methylation workflows ensure precision, compliance, and scale.
Fast Turnaround Time
Optimized workflows deliver results in 2–4 weeks from sample receipt — helping you move from collection to insights without delay.
Sample & Array Flexibility
We process diverse tissue types — including blood, saliva, and solid tissue — and design custom or standard arrays to meet your study’s needs.
TruDiagnostic is the gold standard for epigenetic research.
We don’t just process samples — we partner with you to generate meaningful, publishable, and predictive insights that accelerate discovery and drive results.
What Our Tools Enable
Personalized Health Profiles
Translate static methylation into dynamic, personalized health profiles
Intervention Efficacy
Measure intervention efficacy across biological age, disease risk, immune health, and more
Longitudinal Insights
Generate longitudinal insight from a single dried blood spot
Pattern Discovery
Discover patterns of resilience and dysfunction invisible to conventional diagnostics
While we measure DNA methylation, it’s our algorithms that transform raw data into meaningful biological interpretation.
Our proprietary tools translate methylation signatures into advanced metrics — including biological age, immune composition, disease risk, and predicted clinical biomarkers. This allows researchers and clinicians to see what’s actively unfolding in the body — far beyond what static genetic tests can reveal.
Biological Age Clocks
We offer multiple validated aging algorithms—including OMICmAge, SYMPHONYAge, and DunedinPACE—to quantify biological age, pace of aging, and organ-specific aging. These tools empower studies on longevity interventions, disease prediction, and wellness optimization.
Epigenetic Biomarker Proxies (EBPs)
EBPs are our suite of machine learning models trained to predict traditional clinical biomarkers (e.g., CRP, glucose, NAD+) from methylation signatures. These tools allow you to extract 100+ multi-omic variables from a single sample.
Deconvolution Algorithms
Our immune cell-type deconvolution models infer immune composition directly from methylation data—enabling non-invasive immune profiling and inflammation tracking without additional assays.
Methylation Risk Scores (MRS)
Our next-gen risk stratification tool. MRS models calculate disease probability based on composite methylation signatures—offering predictive power above and beyond genomics alone.
Who We Serve
We collaborate with pioneers across clinical, academic, and commercial fields to push the boundaries of what’s possible in longevity science and preventive health.
Our Impact By The Numbers
6 Trillion
DNA Markers Measured To Date
100,000+
Individuals Tested
115+
Research Partnerships Worldwide
We offer advanced DNA methylation profiling services to academic researchers, clinical practitioners, and commercial partners using Illumina's cutting-edge technology.
Each platform is designed to meet specific research needs, from large-scale population studies to in-depth epigenetic investigations.
As part of our services, we provide reliable, end-to-end support to you – including study design, participant recruitment, grant funding, testing preparation, algorithmic analysis and data interpretation, helping your team unlock deep biological insights with the speed and efficiency of our in-house lab operations.
Interventional Trial Highlights
Our partnerships yield groundbreaking research findings
Yale Interventional Aging Study: Evaluating the effectiveness of 51 diverse aging intervention methods
Nutritarian Diet Studies: Evaluating dietary interventions and their impact on biological age
Senolytic Trials (Dasatinib + Quercetin): Assessing senolytic therapy effects on aging biomarkers
Yale Ketamine Trial: Investigating the impact of ketamine therapy on biological age and mental health
Collaborators
We are proud to partner with over 20 leading academic collaborators worldwide. These collaborations enhance our research capabilities and enable us to tackle complex questions in epigenetics. Together, we are making strides in understanding and improving human health, leveraging the expertise and resources of our esteemed collaborators.
Psychiatric Geneticist, Director of the Center for Biomarker Research and Personalized Medicine
Associate Professor of Psychiatry and Behavioral Sciences
Assistant Professor (Research), Fels Cancer Institute for Personalized Medicine
Professor and Vice Chair of Research
Assistant Professor of Psychiatry
Chair of Suicide Prevention Research
Professor School of Biomedical Sciences and Pharmacy
PhD, Research Scientist
PhD, Research Scientist
Assistant Professor in Medicine-Infectious Disease
Assistant Professor of Psychiatry
Professor School of Biomedical Sciences and Pharmacy
Psychiatric Geneticist, Director of the Center for Biomarker Research and Personalized Medicine
Associate Professor of Psychiatry and Behavioral Sciences
Assistant Professor (Research), Fels Cancer Institute for Personalized Medicine
Chair of Suicide Prevention Research
PhD, Research Scientist
PhD, Research Scientist
Professor and Vice Chair of Research
Assistant Professor in Medicine-Infectious Disease
Psychiatric Geneticist, Director of the Center for Biomarker Research and Personalized Medicine
Associate Professor of Psychiatry and Behavioral Sciences
Assistant Professor (Research), Fels Cancer Institute for Personalized Medicine
Professor and Vice Chair of Research
Assistant Professor of Psychiatry
Chair of Suicide Prevention Research
Professor School of Biomedical Sciences and Pharmacy
PhD, Research Scientist
PhD, Research Scientist
Assistant Professor in Medicine-Infectious Disease
Psychiatric Geneticist, Director of the Center for Biomarker Research and Personalized Medicine
Associate Professor of Psychiatry and Behavioral Sciences
Assistant Professor (Research), Fels Cancer Institute for Personalized Medicine
Professor and Vice Chair of Research
Assistant Professor of Psychiatry
Professor School of Biomedical Sciences and Pharmacy
PhD, Research Scientist
Assistant Professor (Research), Fels Cancer Institute for Personalized Medicine
Psychiatric Geneticist, Director of the Center for Biomarker Research and Personalized Medicine
Professor and Vice Chair of Research
Assistant Professor of Psychiatry
Professor School of Biomedical Sciences and Pharmacy
Associate Professor of Psychiatry and Behavioral Sciences
PhD, Research Scientist
Psychiatric Geneticist, Director of the Center for Biomarker Research and Personalized Medicine
Associate Professor of Psychiatry and Behavioral Sciences
Assistant Professor (Research), Fels Cancer Institute for Personalized Medicine
Professor and Vice Chair of Research
Assistant Professor of Psychiatry
Professor School of Biomedical Sciences and Pharmacy
PhD, Research Scientist
Research Articles
With over 25+ peer-reviewed articles published, our research team is at the forefront of epigenetic studies. Each publication reflects our commitment to advancing scientific knowledge and providing valuable insights into the mechanisms of aging, disease, and health. Our work continues to push the boundaries of what is known, contributing significantly to the scientific community.
15+ Peer-reviewed Studies
With participation in more than 15 peer-reviewed publications, our research stands at the forefront of epigenetics.
20+ Renowned University Partnerships
Renowned universities we actively partner with for research and licensing opportunities.
5+ New Epigenetic Algorithms
New, original, epigenetic algorithms we’ve developed to improve diagnostic accuracy.
15+ Peer-reviewed Studies
With participation in more than 15 peer-reviewed publications, our research stands at the forefront of epigenetics.
20+ Renowned University Partnerships
Renowned universities we actively partner with for research and licensing opportunities.
5+ New Epigenetic Algorithms
New, original, epigenetic algorithms we’ve developed to improve diagnostic accuracy.
Inquiry Form
Interested in partnering with us or learning more about our research capabilities? Please fill out our form below to start the conversation.