Pioneering Epigenetics Through Collaborative Science
We are dedicated to advancing the frontier of epigenetic research by collaborating closely with academic researchers, healthcare providers, clinical institutions, and industry leaders. Our comprehensive, precise, and actionable epigenetic testing empowers researchers to uncover groundbreaking insights into human health and aging.
Why Researchers Choose TruDiagnostic
TruDiagnostic is the gold standard for aging, longevity, and disease prevention research. We don’t just process samples—we partner with you to generate meaningful, publishable, and predictive insights that accelerate discovery and drive results. Every step of the way, our team provides you with expert insights and recommendations to improve.
Whether you're launching a clinical trial, developing a health product, or building a longevity platform, our tools and support infrastructure help you uncover deeper signals from every sample—faster, more affordably, and with more scientific rigor than any university core lab.
Unmatched Accuracy & Precision
High Throughput, Low Cost Processing in Our CLIA Certified Lab
Up to $50 cheaper per sample than university labs, with CLIA-certified, CAP-compliant precision
Recruitment-Ready Database
Access to a growing network of methylation-profiled individuals for future trials and studies
Exclusive Access to 1,000+ Algorithms
Including Epigenetic Biomarker Proxies (EBPs), unavailable anywhere else
Co-Authorship and Collaboration
Our team frequently co-publishes with academic and industry partners in high-impact journals
Free Bioinformatics Support
Includes advanced analysis, visualization, and help with manuscript development
Who We Are
Founded by a coalition of leading medical physicians and scientists, TruDiagnostic is a state-of-the art epigenetic testing company that specializes in biological aging, nutritional deficiencies, and cellular systems health based on DNA methylation
Our impact by the numbers
6 Trillion
DNA Markers Measured To Date
100,000+
Individuals Tested
115+
Research Partnerships Worldwide
An Introduction to Epigenetics
Epigenetics is the study of how lifestyle and environment influence gene expression—without altering the underlying DNA sequence. At the center of this process is DNA methylation, a chemical tag that can turn genes “on” or “off,” guiding how cells function, repair, and age.
Unlike fixed genetic code, methylation patterns are dynamic and responsive—making them one of the most powerful biomarkers for tracking biological aging, disease susceptibility, and therapeutic response. TruDiagnostic measures these patterns at high resolution, providing the foundation for next-generation health insights.
What Our Tools Unlock from DNA Methylation
While we measure DNA methylation, it’s our algorithms that transform raw data into meaningful biological interpretation.
Our proprietary tools translate methylation signatures into advanced metrics—including biological age, immune composition, disease risk, and predicted clinical biomarkers. This allows researchers and clinicians to see what’s actively unfolding in the body—far beyond what static genetic tests can reveal.
Who We Serve
We collaborate with pioneers across clinical, academic, and commercial fields to push the boundaries of what’s possible in longevity science and preventive health.
Our Propriety Algorithms
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Biological Age Clocks
We offer multiple validated aging algorithms—including OMICmAge, SYMPHONYAge, and DunedinPACE—to quantify biological age, pace of aging, and organ-specific aging. These tools empower studies on longevity interventions, disease prediction, and wellness optimization.
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Deconvolution Algorithms
Our immune cell-type deconvolution models infer immune composition directly from methylation data—enabling non-invasive immune profiling and inflammation tracking without additional assays.
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Epigenetic Biomarker Proxies (EBPs)
EBPs are our suite of machine learning models trained to predict traditional clinical biomarkers (e.g., CRP, glucose, NAD+) from methylation signatures. These tools allow you to extract 100+ multi-omic variables from a single sample.
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Methylation Risk Scores (MRS)
Our next-gen risk stratification tool. MRS models calculate disease probability based on composite methylation signatures—offering predictive power above and beyond genomics alone.
Our Propriety Algorithms
Biological Age Clocks
We offer multiple validated aging algorithms—including OMICmAge, SYMPHONYAge, and DunedinPACE—to quantify biological age, pace of aging, and organ-specific aging. These tools empower studies on longevity interventions, disease prediction, and wellness optimization.
Deconvolution Algorithms
Our immune cell-type deconvolution models infer immune composition directly from methylation data—enabling non-invasive immune profiling and inflammation tracking without additional assays.
Epigenetic Biomarker Proxies (EBPs)
EBPs are our suite of machine learning models trained to predict traditional clinical biomarkers (e.g., CRP, glucose, NAD+) from methylation signatures. These tools allow you to extract 100+ multi-omic variables from a single sample.
Methylation Risk Scores (MRS)
Our next-gen risk stratification tool. MRS models calculate disease probability based on composite methylation signatures—offering predictive power above and beyond genomics alone.
What Our Tools Enable
- Translate static methylation into dynamic, personalized health profiles
- Measure intervention efficacy across biological age, disease risk, immune health, and more
- Generate longitudinal insight from a single dried blood spot
- Discover patterns of resilience and dysfunction invisible to conventional diagnostics
Inquiry Form
Interested in partnering with us or learning more about our research capabilities? Please fill out our form below to start the conversation.