A New Era of Medicine Powered by Epigenetics

Empowering clinicians, researchers, and commercial brands with science-backed tools for longevity and disease management.
OVER 80+ academic PARTNERSHIPS
Epigenetic Insights for Every Need

Healthcare Providers

Improve patient outcomes with validated epigenetic testing for earlier insight and personalized care.
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Individuals

Access epigenetic testing directly. Discover key disease, aging, and longevity biomarkers.
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Research & Collaboration

Power your clinical trials with the world’s largest epigenetic database. Backed by 50+ peer-reviewed publications.
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Commercial Partnerships

Integrate epigenetic testing into your platform. White-label solutions for biopharma and wellness platforms.
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Our Tests

Explore our epigenetic tests trusted by leading clinicians and scientists.
Explore our epigenetic tests trusted by leading clinicians and scientists.

TruAge + TruHealth Combination Kit

180+ biomarkers across functional health, aging, and condition management – designed to support truly personalized care.

TruAge

Measure how fast you're aging at the cellular level. 75 epigenetic biomarkers across biological age, aging speed, and organ-specific aging for 11 body systems, including brain, heart, and liver.

TruHealth

Decode your body's functional health. 110 epigenetic biomarkers across nutrition, vitamins, inflammation, metabolic health, toxin burden, and more.
WHY EPIGENETICS?

Epigenetics determines 80% of health outcomes.

Genetics only determine 20% of our health. The rest is in our control. Unlock evidence-based ways to optimize diet, sleep, stress, and more.
Biological Age
Vitamins
Antioxidants
Fatty Acids
Amino Acids
Methylation
Microbiome
Immune Markers
Stress
Oxidative Defense
Neurocognition
Ketones
Mitochondrial Function
Smoking
Death Risk
Metabolism
Inflammation
Toxins
Hormones
Aging Speed
180+ Biomarkers
Traditional labs offer a snapshot of your health in a single moment. TruDiagnostic shows how your biology is evolving over time. By measuring gene expression, our epigenetic testing uncovers long-term biological trends and early disease risks before symptoms arise.
Precision diagnostics powered by whole-genome methylation science.

Measure The Improvement

Our tests tracks meaningful changes in disease risk, age profile, and biological health to help manage chronic conditions and drive better patient outcomes.
UNCOMPROMISING STANDARDS

Clinical-Grade Science Behind Every Result

Our epigenetic testing solutions are trusted by leading clinicians and scientists.
50+
PEER-REVIEWED PUBLICATIONS
A research-first team publishing the science behind every product.
80+
RESEARCH PARTNERSHIPS
Collaborations with renowned universities, hospitals, and commercial partners.
6T+
HUMAN DATA POINTS
One of the world’s largest DNA methylation datasets –smarter with every test.
1M+
DNA SITES
Measured in every test for the most precise, personalized health insights.
TRUDIAGNOSTIC TECHNOLOGY

Epigenetic signatures cut through biological noise, providing clearer, more actionable biomarkers.

The Results of Epigenetic Testing

See how patients may benefit by adding TruAge to your testing.
As a physician herself, Priya wanted to quantify the impact of her longevity protocol, from fasting to zone 2 cardio to targeted supplementation, using hard epigenetic data rather than standard bloodwork alone.
HOW TRUDIAGNOSTIC MAY HELP
Quarterly TruAge testing gave Priya a precise biological measurement to track her protocol against, while TruHealth confirmed her inflammation and metabolic markers were improving. Her aging speed dropped from 0.97 to 0.81 over 3 years, and her biological age now reads 6 years younger.
YEAR 1
0.97
AGING SPEED
BIOLOGICAL AGE
+5 yrs
HEART AGE
+4 yrs
INFLAMMATION
46%
KETONE MARKERS
52%
YEAR 3
0.81
AGING SPEED
BIOLOGICAL AGE
−1 yr
HEART AGE
24%
INFLAMMATION
Optimal
KETONE MARKERS
+1 yr
Jane was struggling with unexplained weight gain and persistent fatigue despite a healthy lifestyle. She wanted data to understand what was driving accelerated aging at the cellular level.
HOW TRUDIAGNOSTIC MAY HELP
TruHealth flagged elevated inflammation and elevated HbA1c that standard bloodwork had not connected, and TruAge showed she was aging 23 percent faster than her calendar age. With a precise target, her care team adjusted her protocol. Three years later her aging speed fell from 1.23 to 0.94 and her biological age flipped from nearly 3 years older to 1 year younger.
YEAR 1
1.23
AGING SPEED
BIOLOGICAL AGE
+2.8 yrs
INFLAMMATION
61%
HbA1c
High
KETONE MARKERS
48%
YEAR 3
0.94
AGING SPEED
BIOLOGICAL AGE
−1 yr
INFLAMMATION
24%
HbA1c
Optimal
KETONE MARKERS
79%
Marcus was crashing every afternoon despite eight hours of sleep. His doctor had ruled out thyroid issues and anemia, but something was clearly off and he needed a deeper look.
HOW TRUDIAGNOSTIC MAY HELP
TruHealth pinpointed the culprit, suboptimal ATP synthesis and elevated inflammation, the cellular energy blockers his standard labs had missed. TruAge confirmed the toll it was taking on his pace of aging. After his provider adjusted his protocol, his ATP synthesis moved from suboptimal to ideal, inflammation dropped by more than half, and his aging speed slowed from 1.15 to 0.93.
YEAR 1
1.15
AGING SPEED
BIOLOGICAL AGE
+3 yrs
ATP SYNTHESIS
Suboptimal
INFLAMMATION
58%
HEART AGE
+2 yrs
YEAR 3
0.93
AGING SPEED
BIOLOGICAL AGE
−1 yr
ATP SYNTHESIS
Ideal
HORMOINFLAMMATIONNE AGE
21%
HEART AGE
−1 yr
David was lying awake for hours every night despite being exhausted. Sleep meds helped in the short term but felt like a band-aid. He wanted to understand the biological root cause instead of just masking it.
HOW TRUDIAGNOSTIC MAY HELP
Through the TruAge and TruHealth Combination Kit, David could see he was biologically 2 years older than his calendar age, and that elevated catecholamine metabolism and systemic inflammation were disrupting his sleep at the cellular level. As his protocol took hold, both markers improved and his aging speed settled from 1.08 to 0.95.
BEFORE
1.08
AGING SPEED
BIOLOGICAL AGE
+2 yrs
VMA CATECHOL
High
INFLAMMATION
54%
HEART AGE
+1 yr
AFTER
0.95
AGING SPEED
BIOLOGICAL AGE
−1 yr
VMA CATECHOL
Optimal
INFLAMMATION
22%
HEART AGE
−1 yr
LONGEVITY
Dr. Priya S.
AGING SPEED
0.97
0.81
CRP
YEAR 1
YEAR 3
BIOLOGICAL AGE
+5 yrs
−1 yr
HEART AGE
+4 yrs
−2 yrs
INFLAMMATION
46%
23%
KETONE MARKERS
52%
76%
As a physician herself, Priya wanted to quantify the impact of her longevity protocol, from fasting to zone 2 cardio to targeted supplementation, using hard epigenetic data rather than standard bloodwork alone.
HOW TRUDIAGNOSTIC MAY HELP
Quarterly TruAge testing gave Priya a precise biological measurement to track her protocol against, while TruHealth confirmed her inflammation and metabolic markers were improving. Her aging speed dropped from 0.97 to 0.81 over 3 years, and her biological age now reads 6 years younger.
WEIGHT LOSS
Jane W.
AGING SPEED
1.23
0.94
CRP
YEAR 1
YEAR 3
BIOLOGICAL AGE
+2.8 yrs
−1 yr
INFLAMMATION
61%
24%
HbA1c
High
Optimal
KETONE MARKERS
48%
79%
Jane was struggling with unexplained weight gain and persistent fatigue despite a healthy lifestyle. She wanted data to understand what was driving accelerated aging at the cellular level.
HOW TRUDIAGNOSTIC MAY HELP
TruHealth flagged elevated inflammation and elevated HbA1c that standard bloodwork had not connected, and TruAge showed she was aging 23 percent faster than her calendar age. With a precise target, her care team adjusted her protocol. Three years later her aging speed fell from 1.23 to 0.94 and her biological age flipped from nearly 3 years older to 1 year younger.
ENERGY & FATIGUE
Marcus T.
AGING SPEED
1.15
0.93
CRP
YEAR 1
YEAR 3
BIOLOGICAL AGE
+3 yrs
−1 yr
ATP SYNTHESIS
Suboptimal
Ideal
INFLAMMATION
58%
21%
HEART AGE
+2 yrs
−1 yr
Marcus was crashing every afternoon despite eight hours of sleep. His doctor had ruled out thyroid issues and anemia, but something was clearly off and he needed a deeper look.
HOW TRUDIAGNOSTIC MAY HELP
TruHealth pinpointed the culprit, suboptimal ATP synthesis and elevated inflammation, the cellular energy blockers his standard labs had missed. TruAge confirmed the toll it was taking on his pace of aging. After his provider adjusted his protocol, his ATP synthesis moved from suboptimal to ideal, inflammation dropped by more than half, and his aging speed slowed from 1.15 to 0.93.
INSOMNIA
David R.
AGING SPEED
1.08
0.95
CRP
YEAR 1
YEAR 3
BIOLOGICAL AGE
−2 yrs
−1 yr
VMA CATECHOL
High
Optimal
INFLAMMATION
54%
22%
HEART AGE
+1 yr
−1 yr
Tyler is already fit but wants proof that his training and recovery choices are adding up to real biological benefit, not just aesthetics. He wants to optimize, not just maintain.
HOW TRUDIAGNOSTIC MAY HELP
TruAge can let him benchmark his biological age, his organ systems through the SYMPHONYAge clocks, and his pace of aging against his training, and fine tune recovery if an organ system like immune age lags. In a profile like Tyler’s, consistent testing could show his aging speed trending down with each organ system tracking younger than his calendar age.
PROVIDING TRUDIAGNOSTIC

Bring Epigenetic Diagnostics Into Your Practice

Join thousands of clinicians and researchers transforming outcomes with TruDiagnostic.
WHAT OUR PARTNERS SAY

Trusted by leading clinicians, researchers, and health organizations worldwide.

Explore core diagnostics, reporting tools, and research platforms trusted by leading clinicians and scientists.
TruDiagnostic is the leader in biological age testing, in my opinion... and I've done the research! The company is backed by science and is relentless in the pursuit of innovation. This is why it is the test of choice for NextHealth.
Dr. Darshan Shah

CEO and Founder of Next Health
Aging is complex but with the right data, it becomes actionable. The TruAge + TruHealth Combination Kit reveals how fast your body is aging, which systems are under strain, and where to focus your interventions. From OMICmAge to telomere length, pace of aging, and immune metrics like CD4/CD8 ratio, it’s the most advanced way to test what’s working and what needs work. I love using it to validate therapies and make each protocol personal.
Dr. Edwin Lee

CEO and Founder of The Institute for Hormonal Balance
The TruAge + TruHealth Combination Kit is a core part of every patient’s yearly assessment. It allows me to measure and monitor their longevity progress over time. There’s no better tool to validate interventions and personalize care and it’s become a key differentiator for my practice.
Dr. Sanjeev Goel

Founder, Peak Human
Epigenetic testing is revolutionizing the way we approach health and longevity. At Biohax, it’s a cornerstone of our protocol — allowing us to go beyond genetics and truly personalize care. It empowers us to track biological aging, reverse dysfunction, and design interventions that enhance human potential at the cellular level. At Biohax, we call that Epigenetic Enhancement Therapy™.
Dr. Marcos de Andrade

Founder of Biohax
TRUDIAGNOSTIC IN THE NEWS

Peer-reviewed. Partnered. Published.

Our science is validated in top-tier journals and trusted by the world’s leading labs, universities, and brands.
PUBLICATION · 2026
OMICmAge: the leading biological age clock.
A Harvard and TruDiagnostic collaboration integrated DNA methylation with multi-omics data to build a clock that predicts chronic disease and mortality — validated in over 14,000 TruDiagnostic samples.
Read the research
PUBLICATION · 2026
DunedinPACE is the strongest individual predictor of all-cause mortality.
In a 7.4-year study of 1,083 older adults, our pace of aging clock outperformed 14 leading longevity biomarkers — including inflammation markers, grip strength, and cognitive tests.
Read the research
PUBLICATION · 2024
Epigenetic biomarkers outperform traditional labs in disease prediction.
Harvard & TruDiagnostic found that epigenetic biomarkers outperform traditional labs by 62%. They offer faster, more comprehensive insights from a single at-home sample.
Read the research
PARTNERSHIP · 2024
R&D partnership with L'Oréal advances beauty and longevity science through epigenomics.
TruDiagnostic and L'Oréal are partnering to decode how epigenetics governs long-term skin and hair aging — moving beyond surface-level skincare to the biology underneath.
Read the research
PUBLICATION · 2024
DeepStrataAge reveals stage- and sex-divergent aging dynamics.
Built on 29,167 DNA methylation samples, DeepStrataAge is the first deep-learning clock to reveal how aging diverges by life stage and biological sex.
Read the research
PUBLICATION · 2024
51 longevity interventions ranked across multiple aging clocks in largest meta-analysis of its kind.
Yale and TruDiagnostic evaluated how therapies, supplements, and lifestyle changes affect epigenetic age.
Read the research

Frequently Asked Questions

Visit Help Center
What is epigenetics?

Your DNA is like a blueprint — it doesn’t change. But epigenetics is the layer on top of it that controls which genes get turned on or off. These signals, called DNA methylation patterns, are shaped by your lifestyle, environment, stress, diet, and age. TruDiagnostic reads these patterns from a single dried blood spot to give you a precise, stable picture of how your body is actually functioning — not just what you inherited.

Who is this test for?

TruDiagnostic is for anyone who wants to understand what’s driving their health at the cellular level — not just manage symptoms. Our customers tend to be proactive about their health: people optimizing their longevity protocol, athletes tracking recovery and performance, patients whose standard labs keep coming back “normal” but still don’t feel right, and anyone who wants a precise biological baseline before making changes to their diet, supplements, or lifestyle.

What do I do with my results?

Your report breaks down each biomarker with a plain-language explanation, a score showing where you fall relative to the population, and specific recommendations — including dietary changes, supplements, and lifestyle interventions — prioritized by what’s most likely to move the needle for you. Many customers share their report with a functional medicine doctor, longevity physician, or health coach to build a personalized action plan.

How accurate are the test results?

TruDiagnostic’s algorithms are validated against the largest DNA methylation database in the world: 100,000+ patients linked to lifetime medical records. Each biomarker is cross-validated against clinical, proteomic, and metabolomic data. Unlike serum tests that fluctuate day to day, epigenetic biomarkers reflect stable, long-term biological patterns, making them highly reproducible and clinically meaningful.

Are TruDiagnostic tests CLIA certified?

Yes. TruDiagnostic operates in a CLIA-certified laboratory, meaning our testing processes meet the federal standards required for clinical diagnostic testing. Every sample is processed under rigorous quality controls to ensure the accuracy and reliability of your results.

Does insurance cover this test?

TruDiagnostic tests are not currently covered by insurance. They are available for direct purchase and are eligible for FSA/HSA reimbursement in most cases. Many customers work with their functional medicine physician or longevity-focused provider to incorporate results into a broader care plan.